Jose Guadalupe Tapia Quintero, guilty of drug trafficking and money laundering. Lupe Tapia was linked to Mayo Zambada, Chapo Guzman and was considered a key operator of the Sinaloa Cartel

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DECEMBER 3, 2025

WRITTEN BY: MIGUEL ANGEL VEGA of RÍODOCE

The Sinaloa cartel leader could face a 15-year sentence in the United States.

Last Wednesday, October 29, José Guadalupe "Lupe" Tapia Quintero had to review one last time the document in which he changed his plea from not guilty to guilty. It contained the crimes he had admitted to prosecutors. Nothing more. That's why he reportedly verified that the word "fentanyl" was not included in the indictment. He also agreed to pay the United States government $10 million.

That sum, equivalent to 187 million pesos at the exchange rate at the time, was, as it would be for any other drug trafficker, weak or powerful, an exorbitant amount. But as has happened with those who came before him, it's always better to pay than to remain locked up in a U.S. prison.

It was then that the San Lorenzo Valley kingpin signed the document and handed it to his lawyer, according to federal agents who have witnessed such scenes. Thus, one of the most powerful drug traffickers in Culiacán between 2005 and 2023 joined the long list of criminals who choose to change their pleas and pay hundreds of millions of pesos to the US in exchange for less severe sentences.

All the accusations he once faced, which led the DEA to label him one of the main poisoners of American society, including charges of fentanyl production and trafficking, illegal possession of firearms, and criminal conspiracy, are now a thing of the past. All of that was removed from the records, as the agreement Lupe Tapia signed at that time only charged him with methamphetamine trafficking and money laundering. And if everything goes as his lawyer has promised, he could be released from prison in no more than 15 years.

“He’s going to do well. Because he made a ton of money trafficking drugs, ice, fentanyl, and cocaine,” said a resident of El Salado, a municipality in Culiacán, who had known him for years.

The Drug Trafficking Route

Lupe Tapia, as those named Guadalupe are known, is originally from Estancia de los García, in Tacuichamona, a district south of Culiacán. Like many farmers from rural areas of Sinaloa, he worked in agriculture. And just as happens with people from areas with little or no social and economic development, he found a goldmine in drug trafficking.

First, the kingpin grew marijuana, then he moved it from one place to another, and life connected him with clients in the US, to whom he sent the drugs. He lived well, but he was just another drug trafficker. But with the rise of synthetic drugs, primarily methamphetamines, or "ice" as the drug traffickers call it, his income grew, and in partnership with Ismael "El Mayo" Zambada, the local kingpin, he went from being "El Lupe" to "Don Lupe," and on a larger scale, Lupe Tapia.

Thanks to a group of informants who collaborated with the United States, the DEA identified him as one of El Mayo Zambada's main associates. He worked alongside his brother, César, but the target was Lupe, as he was considered the mastermind of the brothers.

Investigations by the Ministry of Defense identified him as one of the main producers of fentanyl, according to court documents and press releases issued at the time of his arrest on February 9, 2023.

“The accused is considered the main producer of fentanyl and methamphetamine pills, in addition to carrying out large-scale cocaine trafficking from Central and South America to the United States,” reads the statement from the Ministry of Defense, then known as Sedena.

Since then, Lupe Tapia has remained in the shadows. He is currently incarcerated in a medium-security prison in Phoenix, Arizona, after admitting that between December 2006 and March 2012, he was in charge of coordinating the transportation and distribution of methamphetamine from Mexico to the United States.

Judge Michael Liburdi of the Arizona District Court set the sentencing hearing for February 2, 2026, at which his future will be determined, including the prison where he will serve the remainder of his sentence and how he will pay the $10 million fine.

Regarding this amount, Mark Davis, a former FBI agent, explained that although the money is part of an agreement between the government and the defendant, it is an amount that is unlikely to be recovered. He stated that it is merely a charade to demonstrate to the public that the government is actually impacting convicted drug traffickers and that the so-called "war on drugs" is being taken seriously.

"It's really done because these types of cases receive international press coverage, involve cross-border crime, but they are very complicated processes that rarely recover any assets from drug traffickers," explained the agent, who worked undercover in Mexico, where he led the FBI's hunt for drug traffickers.

 

In Mexico, it is common knowledge that assets It is common knowledge that the assets of drug lords are generally held in the names of third parties, including family members, friends, and other front men.

One Family Among Many

Just like the brothers Lupe and César Tapia Quintero, the latter arrested in August 2023 in the Guadalupe Victoria neighborhood, Lupe Tapia's eldest son, Heibar Josué Tapia, is also behind bars.

The arrest occurred on August 22, 2022, in the Las Mañanitas subdivision, near the Culiacán airport. According to the Defense Ministry, Heibar Josué was an operative for Mayo Zambada. Security in Culiacán

The family has been blacklisted by the U.S. Treasury Department since 2014, identifying them as part of the Sinaloa Cartel's most important drug trafficking group, laundering money for that criminal organization. The Treasury Department prohibits all Americans from conducting any type of business with these drug lords.

Article published on November 30, 2025 in issue 1192 of the weekly Ríodoce.

SOURCE: RIODOCE 

Categories: Arizona, fentanyl, Guadalupe Tapia Quintero, Lupe Tapia, Mayo Zambada Faction, sinaloa cartel